There are many successful gaming based YouTubers out there, but there are none more successful than the guys of Smosh. Ian Hecox and Anthony Padilla have at three separate times had the most subscribed to YouTube channel of all, most recently in August of last year. The pair started on YouTube back in 2005 but have been doing Smosh since 2002. Relying heavily on parodies of popular video games and movies these YouTube millionaires are the shining example of what a great YouTube channel can be. Even if you aren’t a gamer, their videos are always funny and even on the low end have millions of views.