Chelsea Handler and Reese Witherspoon are Hollywood’s blonde and ambition pair of besties. The famous friends played best friends in the action packed comedy, This Means War in 2012 and have appeared inseparable. Witherspoon joined Handler for her After Lately show to assist with some comical skits. They have openly talked about their friendship on Handler’s E! talk show, Chelsea Lately. Handler even joked about the Legally Blonde actress’ run in with the police for being intoxicated along with her husband. In good friendly fashion, Witherspoon and her husband laughed at the skit about their public embarrassment. Only a real friend would turn an unfortunate arrest into something comical, helping the media to move on from it.