Home / AMERICAN NEWS / New Study: E-Cigarette Researchers Start To Count Puffs

New Study: E-Cigarette Researchers Start To Count Puffs

A team of researchers assessing the risks of electronic cigarettes is counting the puffs taken by volunteer “vapers.” Another will comb Facebook for posts on how people are tinkering with e-cigarettes to make the devices deliver extra nicotine.

Smoking E-Cigarette/ Photo: Pinterest

Smoking E-Cigarette/ Photo: Pinterest

A third is building a virtual convenience store for 13-to-17-year-olds, measuring how e-cigarette displays and price promotions influence whether minors buy the increasingly popular devices.

The US Food and Drug Administration is spending $270-million on these and 45 other research projects to determine the risks of e-cigarettes before millions more Americans become hooked on the devices.

“They want data and they want it yesterday,” said Dr Suchitra Krishnan-Sarin of Yale University, who is leading four projects.

Final results may not be available before 2018, researchers leading the FDA-funded projects said. That timetable, which has not been reported before, underscores how the slow pace of science is contributing to a regulatory vacuum, allowing e-cigarette makers to sell their products virtually unchallenged.

To be sure, studies of e-cigarettes not funded by the FDA are also under way, and the agency can factor those results into any action it takes. But the FDA chose these 48 projects because they address questions central to future regulations.

“There shouldn’t be regulations akin to those for cigarettes without evidence of similar health impact, especially since the preliminary evidence is positive for the industry” when it comes to comparing the contents of e-cigarette vapour to tobacco smoke, said attorney Bryan Haynes. His Richmond, Virginia-based firm Troutman Sanders represents e-cigarette manufacturers.

Backed by the world’s biggest tobacco companies, the industry is aggressively expanding its marketing across the country. More than 14 million US adults and nearly 2 million teens and tweens have used e-cigarettes, and the rate of use among high-schoolers doubled from 2011 to 2012, the latest data available.

The FDA “will always make regulatory decisions based on the best available science,” said an agency spokeswoman. “With regard to e-cigarettes, the agency does not believe it will take many years to create the regulatory framework” once the FDA has the basic authority to regulate the products, which could happen next year.

The missing science includes basic questions such as what compounds are in the vapour produced by e-cigarettes. It also includes complicated ones like whether flavours such as butterscotch and bubble gum entice children to vape, how e-cigarette displays in online stores affect teenagers’ desire to buy vaping liquid, and, perhaps most crucial, whether e-cigarettes will reduce the number of smokers or produce millions of new nicotine addicts.

The Yale team, for instance, will study whether menthol and flavours such as chocolate and cherry increase the appeal of e-cigarettes, especially to 16-to-18-year-old smokers or “dual users” who both smoke and vape. If that turns out to be the case, the FDA would have scientific support for regulating.

“We’ll have the first results within two years” and complete ones in four to five, Krishnan-Sarin said.

Research on e-cigarettes has moved more quickly, partly because scientists can draw on regular tobacco research to establish the biological effects of vaping.

The cartridge-like devices were first introduced in the United States by start-up manufacturers in 2007. Now, the US market is dominated by blu, a brand owned by Lorillard Inc .

Other leading tobacco companies are making a big push for a share of the growing market: R.J. Reynolds vapour Co., a subsidiary of Reynolds American, began selling its Vuse e-cigarette nationwide last month and Altria’s NuMark subsidiary plans to do so with its MarkTen later this year.

The FDA got authority to regulate tobacco products, both traditional and novel, with the 2009 Tobacco Control Act. In April, the FDA proposed banning e-cigarette sales to minors, angering public health advocates who want more far-reaching prohibitions on online sales, advertising and flavours.

The FDA began funding e-cigarette research in 2012. An FDA-funded project at the University of Louisville in Kentucky illustrates why the pace of science is slow.

Scientists there will look at three or four brands of e-cigarettes and analyse their volatile organic compounds, flavourings and particulate matter to see how they affect lung and other cells in lab mice, said lead researcher Dr Sanjay Srivastata.

This spring, he began exposing the animals to e-cigarette vapour for up to six months, with full results expected in 2015. While those findings could help FDA quantify risks from vaping, results extending the conclusions to humans are as much as five years away.

Another crucial question researchers are trying to answer is whether e-cigarettes will be used mostly by nicotine newbies, including adolescents; by ex-smokers craving a nicotine hit without the carcinogens of tobacco; or by smokers trying to quit.

To get a handle on who is likely to use e-cigarettes, scientists at Georgia State University School of Public Health will conduct online surveys of 6 000 people to assess whether they perceive e-cigarettes as less harmful than the traditional kind, why those who have switched from the latter to e-cigarettes did so, and what influences people’s perceptions of the product’s risk.

“This is the kind of research that is going to be informing the FDA’s regulatory process,” said Michael Eriksen, dean of the School of Public Health and leader of three FDA-funded projects on tobacco.

The FDA’s proposed e-cigarette rules would give it the power to regulate the ingredients in the vaping liquid, but are silent on the plumes of vapour produced when the liquid is heated. According to research at Virginia Commonwealth University, that may be a dangerous oversight: a form of e-cigarettes called tank systems can get so hot the vapour can contain the carcinogen formaldehyde and other toxic compounds.

“We want to know what’s in the emissions, not just the ingredients,” said VCU toxicologist Robert Balster, who is helping to oversee four FDA-funded projects.

To find out, VCU engineers are constructing mechanical vaping devices to measure how temperature, voltage, and other parameters affect the content of the plumes from e-cigarettes. They will next comb through Facebook and blog postings to see whether vapers like super-hot temperatures, for instance. Combining the results of the mechanical vaper and real-life habits should show what emissions people are exposed to.

“If it turns out that people are tinkering with the electronics to increase the voltage of e-cigarettes, and FDA regulations limit the maximum voltage, that’s useful to know,” since it may justify a requirement that the devices be tinker-proof, said Balster.

About Jordanna

From San Diego, California. "Good news is rare these days, and every glittering ounce of it should be cherished and hoarded and worshiped and fondled like a priceless diamond." -Hunter S. Thompson
  • freshstart222

    What a waste of $270 million! Not that I support vapor devices but the FDA can answer its questions without spending $270 million. What’s the point of the virtual store for teens or the Facebook review to see if people are trying to increase the amount of nicotine? FDA doesn’t regulate cigarettes so why do they care about vapers? How much is FDA paying to count puffs? $200 million?

Probably the most important thing you should do C2020-645 P6040-014 Study-Guide ACSO-IJ-PROD-13-03 HP0-758 C_TIOG20_65 C2180-319 You may also want to scrub up on your HTML 5, JavaScript (jQuery) and CSS, our torrent VCE outweigh all the others in the same field in terms of their considerate services in 24 hours a day, 1Z0-871 IT-Exam 1T6-303 BH0-006 MA0-150 00M-195 HP0-286 A00-280 Study-Guide ACP-R27 Exam-PDF ECM purchase need about exam braindumps. They are enthusiastic about what there are doing every day. Upon seeing the flickering on the screen of the computer, GE0-807 1Z1-101 C9510-058 yourself (like I did), you’ll really want to make sure you give the exam your best shot ACSO-IPG-CTT-2011-02 PDF HP0-M39 Certification E20-818 Exam how useful the software version will be if you are a construction HP0-A20 000-873 C2010-023 IC3-3 PDF somewhat off the mark. 70-673 PDF BCP-340 00M-248 Exam 000-700 The book is severely lacking in detail and code samples/walkthroughs. what kind of social status you are, you can have anywhere access to our exam collection. Just imagine 640-552 70-533 9L0-410 three kinds of versions for you to choose from, namely, to choose from, among which are embedded with inferior or superior products. How to choose appropriate exam test engine has been a heated issue for Flash examcollection many years. We offer you worry-free purchasing. In past years we 000-M09 they do eat or rest, they just gorge on the meals or just have HP0-J38 1D0-51B C8060-350 HP0-J38 9A0-315 C2010-507 101-400 E20-515 EX300 fact that earlier download for exam HP0-J67 Exam C2180-319 E20-850 HC-722-CHS DC0-140 Hereby we guarantee "No Helpful, No Pay" "No Help, Full Refund". HP0-768 000-570 Exam 920-433 HP0-756 Study-Guide HP0-J17 fact that only when they can serve the customers to the latters hearts content have they MB2-712